Comparison of different inactivation methods on the stability of Indian vaccine strains of foot and mouth disease virus
A Sarkar, RPT Selvan, S Kishore, K Ganesh… - Biologicals, 2017 - Elsevier
In this study, the efficiency of binary ethyleneimine (BEI) in combination with formaldehyde
(FA) and glutaraldehyde (GTA) in inactivating the Indian FMDV vaccine strains is compared.
The acceptable safety of virus inactivation was faster and the inactivation rates were
increased many-folds with combination of inactivants than BEI alone. FMDV A was
inactivated rapidly than the other two serotypes with BEI+ FA combination. Inactivation plots
were linear for all the serotypes irrespective of inactivation process. Further, the integrity …
(FA) and glutaraldehyde (GTA) in inactivating the Indian FMDV vaccine strains is compared.
The acceptable safety of virus inactivation was faster and the inactivation rates were
increased many-folds with combination of inactivants than BEI alone. FMDV A was
inactivated rapidly than the other two serotypes with BEI+ FA combination. Inactivation plots
were linear for all the serotypes irrespective of inactivation process. Further, the integrity …
Comparison of different inactivation methods on the stability of Indian vaccine strains of foot and mouth disease virus.
AS Arunava Sarkar, RPT Selvan, SK Subodh Kishore… - 2017 - cabidigitallibrary.org
In this study, the efficiency of binary ethyleneimine (BEI) in combination with formaldehyde
(FA) and glutaraldehyde (GTA) in inactivating the Indian FMDV vaccine strains is compared.
The acceptable safety of virus inactivation was faster and the inactivation rates were
increased many-folds with combination of inactivants than BEI alone. FMDV A was
inactivated rapidly than the other two serotypes with BEI+ FA combination. Inactivation plots
were linear for all the serotypes irrespective of inactivation process. Further, the integrity …
(FA) and glutaraldehyde (GTA) in inactivating the Indian FMDV vaccine strains is compared.
The acceptable safety of virus inactivation was faster and the inactivation rates were
increased many-folds with combination of inactivants than BEI alone. FMDV A was
inactivated rapidly than the other two serotypes with BEI+ FA combination. Inactivation plots
were linear for all the serotypes irrespective of inactivation process. Further, the integrity …
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